منابع مشابه
On Buckling Morphogenesis.
Cell-generated mechanical forces drive many of the tissue movements and rearrangements that are required to transform simple populations of cells into the complex three-dimensional geometries of mature organs. However, mechanical forces do not need to arise from active cellular movements. Recent studies have illuminated the roles of passive forces that result from mechanical instabilities betwe...
متن کاملTissue morphogenesis: a surface buckling mechanism.
Surface patterns can emerge during growth of anisotropic tissues because of surface buckling. This morphogenetic scenario is examined in the present paper based on a simple phenomenological theory of tissue growth. In particular, we show that constrained growth can lead to tissue compression, which in turn may result in surface buckling of the tissue. The latter means the appearance of wavy pat...
متن کاملBMP signaling controls buckling forces to modulate looping morphogenesis of the gut.
Looping of the initially straight embryonic gut tube is an essential aspect of intestinal morphogenesis, permitting proper placement of the lengthy small intestine within the confines of the body cavity. The formation of intestinal loops is highly stereotyped within a given species and results from differential-growth-driven mechanical buckling of the gut tube as it elongates against the constr...
متن کاملBuckling along boundaries of elastic contrast as a mechanism for early vertebrate morphogenesis.
We have investigated the mechanism of formation of the body of a typical vertebrate, the chicken. We find that the body forms initially by folding at boundaries of stiffness contrast. These boundaries are dynamic lines, separating domains of different cell sizes, that are advected in a deterministic thin-film visco-elastic flow. While initially roughly circular, the lines of elastic contrast fo...
متن کاملBuckling Studies on Laminated Composite Skew Plates
This paper presents buckling studies made on skew plates using finite element. The effects of the skew angle, aspect ratio, length-to-thickness-ratio, fibre orientation angle, and numbers of layers in the laminate and laminate sequence on the critical buckling load factor (Kcr) of antisymmetric composite laminates have also been presented. The critical buckling load factor (Kcr) is found to inc...
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ژورنال
عنوان ژورنال: Journal of Biomechanical Engineering
سال: 2016
ISSN: 0148-0731,1528-8951
DOI: 10.1115/1.4032128